DESK REVIEWS | 06.02.03. Please outline the total Years lived with disability (YLDs) due to dementia and the source of these estimates

DESK REVIEW | 06.02.03. Please outline the total Years lived with disability (YLDs) due to dementia and the source of these estimates

We could not find specific data for YLD due to dementia. However, a subnational analysis of the Global Burden of Disease project carried out for Brazil between 1990 and 2016 (GBD 2016, 2018) described an increase in the age-standardised YLD rate of 4.9% (2.3% to 7.7%) for Alzheimer’s disease over the years analysed.

References:

GBD 2016. (2018). Burden of disease in Brazil, 1990-2016: A systematic subnational analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 392. http://dx.doi.org/10.1016/S0140-6736(18)31221-2

The GBD estimates (2019) that the YLD’s due to dementia were 35.7 per 100,000 (IHME, 2019).

References:

Institute for Health Metrics and Evaluation (IHME). (2019).  GBD Compare. Seattle, WA: IHME, University of Washington, Available from http://vizhub.healthdata.org/gbd-compare.

According to the Global Health Data Exchange, the YLD of Alzheimer’s disease and other dementias in Indonesia in 2017 is 139,446.64 (Global Health Data Exchange, 2019).

References:

Global Health Data Exchange. (2019). GBD Results Tool. http://ghdx.healthdata.org/gbd-results-tool

Disability adjusted life years (DALYs) attributed to dementia was 42,739 in 2016, showing an increase of 9.6% (95% UI –0·4 to 26.2) in age-standardised rates from 1990 to 2016 (Nichols et al., 2019).

References:

Nichols, E., Szoeke, C. E. I., Vollset, S. E., Abbasi, N., Abd-Allah, F., Abdela, J., … Murray, C. J. L. (2019). Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 18(1), 88–106. http://doi.org/10.1016/S1474-4422(18)30403-4

 

Of the 10 leading causes of DALYs in Mexico’s older population, seven conditions are age-related, namely diabetes mellitus, ischemic heart disease, chronic kidney disease, and other organ diseases, Alzheimer’s disease and other dementias, cerebrovascular diseases, and chronic obstructive pulmonary disease. Alzheimer’s and other dementias represent the fifth main cause of DALYS (disability-adjusted life-years) in Mexican older persons (Parra-Rodríguez et al., 2019). However, no accurate data is available on the total deaths due to dementia.

References:

Parra-Rodríguez, L., González-Meljem, J. M., Gómez-Dantés, H., Gutiérrez-Robledo, L. M., López-Ortega, M., García-Peña, C., & Medina-Campos, R. H. (2019). The Burden of Disease in Mexican Older Adults: Premature Mortality Challenging a  Limited-Resource Health System. Journal of Aging and Health, 898264319836514. https://doi.org/10.1177/0898264319836514