DESK REVIEWS | 06.02.02. Please outline the total deaths and Years of Life Lost (YLL) due to dementia and the source of these estimates

DESK REVIEW | 06.02.02. Please outline the total deaths and Years of Life Lost (YLL) due to dementia and the source of these estimates

According to a study published in 2019 that systematically analysed data from the Global Burden of Disease Study 2016, there were 80,600 deaths (69,174 to 94,940; 95% confidence interval) due to dementia in Brazil in 2016 (GBD 2016, 2019). We could not find specific data for YLL. However, a subnational analysis of the Global Burden of Disease carried out for Brazil (from 1990 to 2016) described a small and non-significant increase in the age-standardised YLL rate of 2.7% (-1.3% to 7.0%) for Alzheimer’s disease over the observed period (GBD 2016, 2018).

References:

GBD 2016. (2018). Burden of disease in Brazil, 1990-2016: A systematic subnational analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 392. http://dx.doi.org/10.1016/S0140-6736(18)31221-2

GBD 2016. (2019). Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 18, 88–106. http://dx.doi.org/10.1016/S1474-4422(18)30403-4

As per the Global Burden of Disease (GBD) study (India State-Level Disease Burden Initiative Neurological Disorders Collaborators, 2021), an estimated 129,000 deaths were attributed to Alzheimer’s disease and other dementias in 2019. GBD estimates (2019) indicate there were 117.14 Years of Life Lost (YLL’s) per 100,000 due to dementia (IHME, 2019).

References:

India State-Level Disease Burden Initiative Neurological Disorders Collaborators (2021). The burden of neurological disorders across the states of India: The Global Burden of Disease Study 1990-2019. The Lancet. Global health, 9(8), e1129–e1144.

Institute for Health Metrics and Evaluation (IHME) (2019).  GBD Compare. Seattle, WA: IHME, University of Washington, Available from http://vizhub.healthdata.org/gbd-compare.

According to the Global Health Data Exchange, the YLL of Alzheimer’s disease and other dementias in Indonesia in 2017 is 522,067.55 (Global Health Data Exchange, 2019).

References:

Global Health Data Exchange. (2019). GBD Results Tool. http://ghdx.healthdata.org/gbd-results-tool

A total of 3205 deaths were attributed to dementia in 2016 showing an increase of 15.3% (95% UI 2.0 to 43.5) in age-standardised rates from 1990 to 2016 (Nichols et al., 2019). However, there is no information on YLL due to dementia specifically for Kenya.

References:

Nichols, E., Szoeke, C. E. I., Vollset, S. E., Abbasi, N., Abd-Allah, F., Abdela, J., … Murray, C. J. L. (2019). Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology, 18(1), 88–106. http://doi.org/10.1016/S1474-4422(18)30403-4

This information is not available.